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Tequila cocktails are closely associated with Mexico, where tequila originated from. The most well known of all tequila cocktails is the classic Margarita which is a simple mix of tequila, orange liqueur and lemon. Other cocktails with tequila that have become popular include the Salty Dog and the Tequila Sunrise. Cocktails with tequila often use certain ingredients to neutralize the strong bite of the tequila.